Pre-Seed is the only lubricant formulated by a woman Sperm Physiologist.
Meet Dr. E and learn more about her research.
Over the past decade, there has been a great deal of data generated by scientists and clinicians confirming the safety of Pre-Seed lubricant's formula. This includes data published in peer-reviewed journals or as presentations at major medical meetings. Pre-Seed lubricant is covered by numerous issued U.S. and international patents.
Click on the selected study title below to view study summaries.
Sperm Toxicity of ‘Nonspermicidal’ Lubricant and Ultrasound Gels Used in Reproductive Medicine.
Fertility & Sterility. 2011;95:835-836
Quantitative Perceptual Differences Among Over-the-Counter Vaginal Products
Using a Standardized Methodology.
Contraception. 2011;84:184-193
Safety and Anti-HIV Activity of Over-the-Counter Lubricant Gels.
International Microbicides Conference 2010 Abstract #347
Mucosal Irritation Potential of Personal Lubricants Relates to Product Osmolality
as Detected by the Slug Mucosal Irritation Assay.
Sexually Transmitted Diseases. 2008 May;35:512-516
Effect of Vaginal Lubricants on Sperm Motility and Chromatin Integrity:
A Prospective Comparative Study.
Fertility & Sterility. 2008 Feb;89:375-379
Prevalence of Vaginal Dryness in Trying-to-Conceive Couples.
Pacific Coast Reproductive Society, April 2003
Products for Sexual Lubrication: Understanding and Addressing Options With Your Patients.
Nursing for Women’s Health. 2011 Jun/Jul;15:253-257
Optimizing Natural Fertility.
Fertility & Sterility. 2008 Nov;90(Suppl 3):S1-S6
Dyspareunia and Vaginal Dryness after Breast Cancer Treatment.
SRM Sexuality, Reproduction & Menopause. 2008 Aug;6:18-22
In this reference book for cancer care providers, Pre-Seed is listed as a water-soluble lubricant that does not decrease sperm motility.
In this medical text written by well-renowned experts, Dr. Craig Niederberger writes: "Virtually all lubricants impair sperm, including saliva. However, some couples need lubricants for intercourse. A recent survey of the effects of various lubricants on sperm motility and DNA quality suggested that Pre-Seed appears to have the least negative effect on sperm.”
The chapter on the initial consultation for male infertility states: "In 2008, in vitro studies suggest that a newer commercially available hydroxyethylcellulose-based lubricant, such as Pre-Seed, has minimal deleterious effects on mobility and sperm chromatin integrity.”
In this classic textbook for medical students, the authors write: "Lubricants may be toxic to sperm. A nontoxic lubricant, Preseed, has been developed for infertile couples."
In this laboratory guide, the authors state: "If a lubricant must be used then it must not show any toxicity to spermatozoa. Currently, the only suitable commercial product for this particular purpose is Pre’, an external use version of the Pre-Seed vaginal lubricant…"
In this book for nursing professionals, Pre-Seed is listed as a water-soluble lubricant that can reduce discomfort during intercourse.
